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Medical Term:

hemoglobin anti-Lepore


Definition: a group of abnormal hemoglobins similar to hemoglobin Lepore. These hemoglobins have normal α chains, but the non-α chain consists of the N-terminal portion of the β chain joined to the C-terminal portion of the ΄ chain. This is the opposite crossing over pattern observed in hemoglobin Lepore. Examples of hemoglobin anti-Lepore include HbMiyada, Hb PCongo, Hb PNilotic, and HbLincoln Park. There is also one variant that is both hemoglobin Lepore and hemoglobin anti-Lepore (HbParchman).