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Pronunciation: he'be-fre'ne-a, heb'e-

Definition: A syndrome characterized by shallow and inappropriate affect, giggling, and silly regressive behavior and mannerisms; a subtype of schizophrenia now renamed disorganized schizophrenia.

[G. hebe, puberty, + phren, the mind]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.