Skip to Content

heavy chain


Definition: a polypeptide chain a subunit of an immunoglobulin molecule, of high molecular weight, such as the γ, α, μ, ΄, or ε chains, determining the immunoglobulin class and subclass. This chain also determines whether complement can be bound and whether the chain can pass through the placenta. There are two identical chains in each immunoglobulin.

Synonym(s): H chain

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.