Definition: A group of a2-globulins in human serum, so called because of their ability to combine with hemoglobin, preventing loss in the urine; variant types form a polymorphic system, with a- and ß-polypeptide chains controlled by separate genetic loci. Levels are decreased in hemolytic disorders and increased in inflammatory conditions or with tissue damage.
[G. hapto, to grasp, + hemoglobin]
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