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haptoglobin

Pronunciation: hap'to-glo'bin

Definition: A group of a2-globulins in human serum, so called because of their ability to combine with hemoglobin, preventing loss in the urine; variant types form a polymorphic system, with a- and ß-polypeptide chains controlled by separate genetic loci. Levels are decreased in hemolytic disorders and increased in inflammatory conditions or with tissue damage.

[G. hapto, to grasp, + hemoglobin]

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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