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Hand-Schüller-Christian disease

Pronunciation: hand shel'er kris'chen

Definition: the chronic disseminated form of Langerhans cell histiocytosis. The classic triad of signs consists of diabetes insipidus, exophthalmos, and bony lesions composed of histiocytes.

Synonym(s): Christian disease1, Christian syndrome, normal cholesteremic xanthomatosis, Schüller disease, Schüller syndrome

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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