Skip to Content
Medical Term:

H-Y antigen


Definition: an antigen factor, dependent on the Y chromosome, responsible for the differentiation of the human embryo into the male phenotype by inducing the initially bipotential embryonic gonad to develop into a testis; in the absence of this antigen, the indifferent gonad develops into an ovary. There are at least two loci involved, an autosomal gene that generates the antigen [MIM*143170] and one that makes the receptor [MIM*143150].

© Copyright 2016 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.