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glycerophosphate shuttle

 

Definition: a mechanism for the transfer of reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesize glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle; found in brain tissue, brown adipose tissue, and white muscle.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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