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?-glutamylcysteine synthetase

 

Definition: an enzyme that catalyzes the first step in glutathione biosynthesis, reacting l-glutamate, l-cysteine, and ATP to form ?-glutamylcysteine, ADP, and orthophosphate; inhibited by thiols such as glutathione and cysteamine.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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