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glutamate dehydrogenases


Definition: enzymes that catalyze the reaction of l-glutamate, H2O, and NAD+ (or NADP+ in some cases) producing a-ketoglutarate (2-oxoglutarate), ammonia, and NADH; in mammals, this is the prime contributor to oxidative deamination.

Synonym(s): glutamic acid dehydrogenases

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.