Skip to Content
Medical Term:

glutamate decarboxylase


Definition: a carboxy-lyase converting l-glutamate to 4-aminobutyrate and CO2 as well as l-aspartate to 3-aminopropanoate and CO2; a defect in the binding of this protein's coenzyme is believed to cause pyridoxine dependency with seizures.

Synonym(s): aspartate 1-decarboxylase

© Copyright 2016 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.