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glutamate decarboxylase

 

Definition: a carboxy-lyase converting l-glutamate to 4-aminobutyrate and CO2 as well as l-aspartate to 3-aminopropanoate and CO2; a defect in the binding of this protein's coenzyme is believed to cause pyridoxine dependency with seizures.

Synonym(s): aspartate 1-decarboxylase

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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