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glucocorticoid resistance


Definition: defective response of target tissues to glucocorticoids; a common acquired state frequently associated with allergic or autoimmune conditions (asthma or rheumatoid arthritis) or severe inflammatory states (respiratory distress syndrome or septic shock); also occurs as a rare genetic syndrome resulting from malfunction of glucocorticoid receptor.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.