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Pronunciation: glob'yu-lin

Definition: Name for a family of proteins precipitated from plasma (or serum) by half-saturation with ammonium sulfate (addition of an equal volume of saturated ammonium sulfate). Globulins may be further fractionated by solubility, electrophoresis, ultracentrifugation, and other separation methods into many subgroups. The main groups are a-, ß-, and ?-globulin, which contain most antibodies.

[L. globulus, globule]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.