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Medical Term:

genetic burden


the genetic debt due to harmful mutation but as yet undischarged. (In a large population of fixed size every mutation with diminished genetic fitness will eventually become extinct, and depending on the details of inheritance and phenotype, must be paid for by a fixed number of genetic deaths per mutation, the genetic debt.)

© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.