general adaptation syndrome
a syndrome introduced by Hans Selye to describe a single marked physiologic response in the pituitary-adrenal system, as a result of exposure to a variety of prolonged physical or psychological stresses or stressors, with the bodily changes progressing through three stages that the author described as the alarm reaction, resistance, and finally exhaustion.
Synonym(s): adaptation syndrome of Selye
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Examples: glitazone, GI cocktail, etc.