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gastrins

Pronunciation: gas'trinz

Definition: Hormones secreted in the pyloric-antral mucosa of the mammalian stomach that stimulate secretion of HCl by the parietal cells of the gastric glands; there are three main types: big gastrin (34 aminoacyl residues), little gastrin (17 residues), and minigastrin (14 residues), as well as sulfated derivatives. The C-terminal pentapeptide is also seen in cholecystokinin and cerulein.

[G. gaster, stomach, + -in]

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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