Definition: gangrene occurring in a wound infected with various anaerobic spore-forming bacteria, especially Clostridium perfringens and C. novyi, which cause rapidly advancing crepitation of the surrounding tissues, due to gas liberated by bacterial fermentation, and constitutional toxic and septic symptoms including cytotoxic damage to kidney, liver, and other organs.
Synonym(s): clostridial myonecrosis, emphysematous gangrene, gangrenous emphysema, progressive emphysematous necrosis
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