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Pronunciation: gang'gren


  1. Necrosis due to obstruction, loss, or diminution of blood supply; it may be localized to a small area or involve an entire extremity or organ (bowel), and may be wet or dry.
  2. Extensive necrosis from any cause, gas gangrene.

Synonym(s): mortification

[G. gangraina, an eating sore, fr. grao, to gnaw]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.