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Pronunciation: gang'gle-o-sid

Definition: A glycosphingolipid chemically similar to cerebrosides but containing one or more sialic (N-acetylneuraminic or N-glycolylneuraminic) acid residues; found principally in nerve tissue, spleen, and thymus; ganglioside GM1 accumulates in generalized gangliosidosis; GM2 accumulates in Tay-Sachs disease.

Synonym(s): sialoglycosphingolipid

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.