Definition: A fluorescent indicator that binds calcium; it is excited at longer wavelengths when free of calcium than when calcium is bound; the ratio of fluorescence intensity at two excitation wavelengths provides a measure of free calcium ion concentration; may be injected into cells to monitor moment-to-moment changes in intracellular free calcium ion concentration.
See Also: aequorin
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Examples: glitazone, GI cocktail, etc.