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fumarate hydratase

Pronunciation: fu'ma-rat hi'dra-tas

Definition: An enzyme catalyzing the reversible interconversion of fumarate and water to malate, a reaction of importance in the tricarboxylic acid cycle. A deficiency will lead to mental retardation.

Synonym(s): fumarase

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.