Pronunciation: fruk'tos bis-fos'fa-tas
Definition: A hydrolase that catalyzes conversion of fructose 1,6-bisphosphate to d-fructose 6-phosphate and orthophosphate in gluconeogenesis; AMP is an allosteric inhibitor; fructose-bisphosphatase deficiency results in problems with impaired gluconeogenesis; there is a similar enzyme that acts on fructose 2,6-bisphosphate.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.