Definition: a radical in its (usually transient) uncombined state; an atom or atom group carrying an unpaired electron and no charge; e.g., hydroxyl and methyl Free radicals may be involved as short-lived, highly active intermediates in various reactions in living tissue, notably in photosynthesis. The free radical nitric oxide, NO·, plays an important role in vasodilation.
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Examples: glitazone, GI cocktail, etc.