Definition: A prognostic assessment developed in the prospective Framingham cohort to estimate cardiovascular risk over a 10-year time span. The most recent version takes into account age, gender, total cholesterol level, high-density-lipoprotein level, cholesterol level, smoking status, systolic blood pressure, and previous medical treatment for hypertension. A calculated 10-year risk for a cardiovascular event of <10% is deemed as being low, 10% to <20% intermediate and =20% high.
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Examples: glitazone, GI cocktail, etc.