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fragile site

 

Definition: a nonstaining gap at a specific point on a chromosome, usually involving both chromatids, always at the same point on chromosomes of different cells from an individual or kindred; it results in in vitro production of acentric fragments, deleted chromosomes, or other chromosome anomalies; inherited as a dominant chromosome marker.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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