Definition: occurrence of numerous, relatively small or tiny, fairly well-circumscribed, usually spheroidal portions of tissue that manifest coagulative, caseous, or gummatous necrosis and are characteristically associated with agents that are hematogenously disseminated; frequently observed only in histologic sections, but the foci may be as large as 1–3 mm and macroscopically visible; arbitrarily, foci larger than that are usually not termed focal necrosis.
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