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Pronunciation: fip-ro'nil

Definition: A phenylpyrazole parasiticide agent that is available as pourable topical solution and spray for flea and tick infestation in dogs and cats; mechanism of action is to disrupt chloride passage through gamma amino butyric acid–mediated channels in nerve cell membranes, resulting in terminal neurologic malfunction. Commercial solutions are flammable.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.