Definition: the offspring of a genetically specified mating: first filial generation (symbol F1), the offspring of parents of contrasting genotypes; second filial generation (F2), the offspring of two F1 individuals; third filial generation (F3), fourth filial generation (F4), etc., the offspring in succeeding generations of continued inbreeding of F1 descendents.
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Examples: glitazone, GI cocktail, etc.