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filaggrin

Pronunciation: fil-ag'grin

Definition: A major protein of the keratohyalin granule, composed mostly of l-histidyl, l-lysyl, and l-arginyl residues (stratum corneum basic proteins). It aggregates keratin intermediate filaments and promotes disulfide bond formation.

[filament + aggregating]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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