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Pronunciation: fi-brin'o-jen

Definition: A globulin of the blood plasma converted into fibrin by the action of thrombin in the presence of ionized calcium to produce coagulation of the blood; the only coagulable protein in the blood plasma of vertebrates; it is absent in afibrinogenemia and is defective in dysfibrinogenemia.

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© Copyright 2019 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.