- The presence of openings or fenestrae in a part.
- Making openings in a dressing to allow inspection of the parts.
- In dentistry, a surgical perforation of the mucoperiosteum and alveolar process to expose the root tip of a tooth to permit drainage of tissue exudate.
- An operation to create an opening in the horizontal semicircular canal to improve hearing in otosclerosis.
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Examples: glitazone, GI cocktail, etc.