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familial partial lipodystrophy


Definition: a disorder characterized by symmetric truncal and extremity lipodystrophy. Findings include full and rounded face, xanthomata, acanthosis nigricans, and insulin-resistant hyperglycemia. In affected patients, fat accumulates around neck, shoulders, and genitalia.

Synonym(s): Dunnigan lipodystrophy, Kobberling-Dunnigan syndrome

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.