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familial hyperlipoproteinemia type IV


Definition: plasma levels of VLDL, pre-ß-lipoproteins and triglycerides are increased on a normal diet, but ß-lipoproteins, cholesterol, and phospholipids are normal; hypertriglyceridemia is induced by a high carbohydrate diet; may be accompanied by abnormal glucose tolerance and susceptibility to ischemic heart disease; probably autosomal dominant inheritance but genetic heterogeneity is a possibility.

Synonym(s): carbohydrate-induced hyperlipemia, familial hyperprebetalipoproteinemia, familial hypertriglyceridemia2

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.