Definition: in the clotting of blood, also known as glass factor and Hageman factor When activated by glass or otherwise to its active form, factor XIIa (EC 126.96.36.199), a serine proteinase, it activates factors VII and XI and converts factor XI to its active form, factor XIa. Deficiency of factor XII results in great prolongation of the clotting time of venous blood, but only rarely in a hemorrhagic tendency; deficiency is caused by an autosomal recessive gene.
Synonym(s): glass factor, Hageman factor
Disclaimer: This site is designed to offer information for general educational purposes only. The health information furnished on this site and the interactive responses are not intended to be professional advice and are not intended to replace personal consultation with a qualified physician, pharmacist, or other healthcare professional. You must always seek the advice of a professional for questions related to a disease, disease symptoms, and appropriate therapeutic treatments.
Search Stedman's Medical Dictionary
Examples: glitazone, GI cocktail, etc.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.