Definition: the association of G-actin subunits into a fibrous (F) protein caused by an increase in salt concentration; the conversion of G-actin to F-actin is catalyzed by small concentrations of magnesium ion, is reversible, and is accompanied by the conversion of the bound ATP molecule to ADP and phosphate and the conversion of one reactive -thiol group to an unreactive form.
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Examples: glitazone, GI cocktail, etc.