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ETS-domain family


Definition: a family of transcription factors, characterized by an evolutionally conserved ETS-domain. Transcription factors play an important role in cell development, differentiation, proliferation, apoptosis, and tissue remodeling. Several ETS genes are rearranged in human leukemia and Ewing tumors.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.