Definition: A type of American leishmaniasis caused by Leishmania braziliensis that affects the mucous membranes, particularly in the nasal and oral region, resulting in grossly destructive changes; particularly common in the Amazon basin, where a significant proportion of people infected with L. braziliensis develop this condition; may develop metastatically from sores originally found elsewhere on the body.
[Sp., fr. L. spongia, sponge]
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Examples: glitazone, GI cocktail, etc.