erythema nodosum leprosum
Definition: an acute type of lepromatous reaction with generalized systemic involvement and tender deep cutaneous and subcutaneous nodules of the face, thighs, and arms; usually seen in undiagnosed, untreated, or neglected cases of leprosy. Immune complexes and scanty, fragmented lepra bacilli may be seen in the lesions.
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Examples: glitazone, GI cocktail, etc.