Definition: An alkaloid from ergot, used to relieve migraine; it is a potent stimulant of smooth muscle, particularly of the blood vessels and the uterus, and produces adrenergic blockade (chiefly of the alpha receptors); hydrogenated ergotamine, dihydroergotamine, is less toxic and has fewer side effects. Also available as ergotamine tartrate.
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Examples: glitazone, GI cocktail, etc.