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Erdheim-Chester disease

Pronunciation: erd'him-ches'ter

Definition: rare systemic disorder characterized by proliferation of histocytes, by symmetric sclerosis at diametaphysial portions of lower limbs, and by extraskeletal involvement. Microscopically, infiltration of affected organs by lipophages and Touton giant cells is evident.

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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