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epithelial membrane antigen


Definition: a heavily glycosylated, 70-kD protein complex, first isolated in human milk fat globulin; this antigen is present in a variety of glandular epithelia, especially in breast carcinoma cells but may also be seen in cultured fibroblasts, lymphoid cells, and some stromal cells. Immunohistochemical staining may aid in tissue diagnosis.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.