Skip to Content


Pronunciation: ep'i-nu're-um

Definition: The outermost supporting structure of peripheral nerve trunks, consisting of a condensation of areolar connective tissue; subdivided into those layers that surround the whole nerve trunk (epifascicular epineurium), and those layers that extend between the nerve fascicles (interfascicular epineurium). With the endoneurium and perineurium, the epineurium comprises the peripheral nerve stroma.

[epi- + G. neuron, nerve]

Disclaimer: This site is designed to offer information for general educational purposes only. The health information furnished on this site and the interactive responses are not intended to be professional advice and are not intended to replace personal consultation with a qualified physician, pharmacist, or other healthcare professional. You must always seek the advice of a professional for questions related to a disease, disease symptoms, and appropriate therapeutic treatments.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.