Definition: The outermost supporting structure of peripheral nerve trunks, consisting of a condensation of areolar connective tissue; subdivided into those layers that surround the whole nerve trunk (epifascicular epineurium), and those layers that extend between the nerve fascicles (interfascicular epineurium). With the endoneurium and perineurium, the epineurium comprises the peripheral nerve stroma.
[epi- + G. neuron, nerve]
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