Skip to Content


Pronunciation: en'do-nu're-um

Definition: The innermost connective tissue supportive structure of nerve trunks, surrounding individual myelinated and unmyelinated nerve fibers; consists principally of ground substance, collagen, and fibroblasts; with the perineurium and epineurium, composes the peripheral nerve stroma.

Synonym(s): Henle sheath, sheath of Key and Retzius

[endo- + G. neuron, nerve]

Disclaimer: This site is designed to offer information for general educational purposes only. The health information furnished on this site and the interactive responses are not intended to be professional advice and are not intended to replace personal consultation with a qualified physician, pharmacist, or other healthcare professional. You must always seek the advice of a professional for questions related to a disease, disease symptoms, and appropriate therapeutic treatments.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.