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Medical Term:


Pronunciation: en'do-nu're-um

Definition: The innermost connective tissue supportive structure of nerve trunks, surrounding individual myelinated and unmyelinated nerve fibers; consists principally of ground substance, collagen, and fibroblasts; with the perineurium and epineurium, composes the peripheral nerve stroma.

Synonym(s): Henle sheath, sheath of Key and Retzius

[endo- + G. neuron, nerve]

© Copyright 2016 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.