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Pronunciation: el'e-fan-ti'a-sis

Definition: Hypertrophy, edema, and fibrosis of the skin and subcutaneous tissue, especially of the lower limbs and genitalia with hydrocele, or enlargement of a limb, usually caused by long-standing obstructed lymphatic vessels, most commonly the result of years of infection by filarial worms such as Wuchereria bancrofti or Brugia malayi.

Synonym(s): elephant leg

[G. fr. elephas, elephant]

See Also: filariasis

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.