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Economo von San Serff disease

Pronunciation: e-kon-o'mo von sahn serf

Definition: a unique encephalitis, presumably viral in origin, which followed the influenza pandemic of 1914–1918. Symptoms included ophthalmoplegia and marked somnolence, and in many survivors, the delayed development of Parkinson disease; the basis for postencephalitic Parkinsonism.

Synonym(s): encephalitis lethargica, polioencephalitis infectiva

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.