Definition: A class of antifungal compounds targeting the fungal cell wall. Action is by specific and noncompetitive inhibition of the (1,3)-ß-d-glucan synthase enzyme complex that forms glucan polymers; a major component of the fungal cell wall in several pathogenic fungi.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.
Search Stedman's Medical Dictionary
Examples: glitazone, GI cocktail, etc.