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echinocandin

Pronunciation: e-ki-no-kan'din

Definition: A class of antifungal compounds targeting the fungal cell wall. Action is by specific and noncompetitive inhibition of the (1,3)-ß-d-glucan synthase enzyme complex that forms glucan polymers; a major component of the fungal cell wall in several pathogenic fungi.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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