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Duchenne dystrophy

Pronunciation: du-shen'

Definition: the most common childhood muscular dystrophy, with onset usually before age 6 years. Characterized by symmetric weakness and wasting of first the pelvic and crural muscles and then the pectoral and proximal upper extremity muscles; pseudohypertrophy of some muscles, especially the calf; heart involvement; sometimes mild mental retardation; progressive course and early death, usually in adolescence. X-linked inheritance (affects males and transmitted by females).

Synonym(s): childhood muscular dystrophy, Duchenne disease, Duchenne muscular dystrophy, pseudohypertrophic muscular dystrophy

Further information

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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