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dopamine ß-monooxygenase

Pronunciation: do'pa-men mon'o-oks'i-jen-as

Definition: A copper-containing enzyme catalyzing oxidation of ascorbate and 3,4-dihydroxyphenylethylamine simultaneously by O2 to yield norepinephrine, dehydroascorbate, and water; a crucial step in catecholamine metabolism. The enzyme is stimulated by fumarate.

Synonym(s): dopamine ß-hydroxylase

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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