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disulfiram

Pronunciation: di-sul'fi-ram

Definition: An antioxidant that interferes with the normal metabolic degradation of alcohol in the body, resulting in increased acetaldehyde concentrations in blood and tissues. Used in the treatment of chronic alcoholism; when taken regularly in chronic alcoholism, it can lower the risk of relapse by inducing severe malaise and nausea if alcohol is consumed. Also used as a chelator in copper and nickel poisoning.

Synonym(s): tetraethylthiuram disulfide

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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