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Medical Term:

disulfiram

Pronunciation: di-sul'fi-ram

Definition

An antioxidant that interferes with the normal metabolic degradation of alcohol in the body, resulting in increased acetaldehyde concentrations in blood and tissues. Used in the treatment of chronic alcoholism; when taken regularly in chronic alcoholism, it can lower the risk of relapse by inducing severe malaise and nausea if alcohol is consumed. Also used as a chelator in copper and nickel poisoning.

Synonym(s): tetraethylthiuram disulfide

© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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