disseminated intravascular coagulation
Definition: a hemorrhagic syndrome that occurs following the uncontrolled activation of clotting factors and fibrinolytic enzymes throughout small blood vessels; fibrin is deposited, platelets and clotting factors are consumed, and fibrin degradation products inhibit fibrin polymerization, resulting in tissue necrosis and bleeding.
See Also: consumption coagulopathy, fibrinogen-fibrin conversion syndrome
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