Definition: gingivitis exacerbated by long-term therapy with diphenylhydantoin; the host response to bacterial plaque is characterized by marked hyperplasia of the fibrous connective tissue and, to a lesser degree, of the surface epithelium, resulting in gross enlargement of interdental papillae that may coalesce and obscure the crowns of the teeth.
Synonym(s): dilantin gingivitis
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Examples: glitazone, GI cocktail, etc.